Prevention by selenium supplementation of cyclosporin-A-induced vascular toxicity
نویسندگان
چکیده
منابع مشابه
Prevention of liquid-diet-induced damages on submandibular glands by selenium supplementation in rats.
This study was designed to explore the protective effects of selenium on submandibular glands of rats that were maintained on liquid diet. The animals kept on liquid diet for 10 days following 20 days of solid diet, had severe degeneration on both acinar and ductal cells: pycnotic nuclei, enlarged granular endoplasmic reticulum, swollen mitochondria with separated cristae, reduction of secretor...
متن کاملSelenium safeguards the liver against 5flurouracil-induced toxicity
Hepatotoxic effect of 5-Fluourouracil (5-FU) can deprive cancer patients of maximum therapeutic benefits. Aim: This study assessed the ability of selenium (Se) to protect against hepatotoxicity induced by 5-FU in rats. Forty adult albino rats were groups and used. Rats in group A (control) were treated intraperitoneally (ip) with 0.2ml of normal saline daily for 5 days. Rats in groups B1-B3 wer...
متن کاملSelenium supplementation for the primary prevention of cardiovascular disease.
This is the protocol for a review and there is no abstract. The objectives are as follows: The primary objective is to determine the effectiveness of selenium only supplementation for the primary prevention of CVD. We will also determine potential adverse effects of selenium only supplementation on major CVD risk factors, such as blood pressure, blood lipids and type 2 diabetes. Results will be...
متن کاملSelenium in the Prevention of Anthracycline-Induced Cardiac Toxicity in Children with Cancer
High cumulative doses of anthracyclines (300-500 mg/m(2)) used in the treatment of children with cancer may result in cardiotoxicity, a major long-term adverse effect that limits clinical usefulness of this class of chemotherapeutic agents. We assessed anthracycline-induced cardiotoxicity by measuring Pro-BNP levels and echocardiographic (ECHO) findings and investigated potential protective eff...
متن کاملSTRUCTURAL ANALYSIS OF CYCLOSPORIN-A BY RAMAN TECHNIQUE
The Raman spectrum of cyclosporin-A has been recorded in the solid phase. The conformation of the molecule has been discussed on the basis of Raman data. It has been concluded that in agreement with X-ray data, cyclosporin-A molecule has an antiparallel P- pleated sheet conformation. It may have some reverse P- turn structure in what has been assigned to a random coil conformation.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cardiovascular Research
سال: 1997
ISSN: 0008-6363
DOI: 10.1016/s0008-6363(97)00008-4